5-MeO-DMT is not on the schedules of the United Nations Convention on Psychotropic Substances of 1971, the treaty that sets the international baseline for controlling psychoactive drugs. That means it is not controlled internationally, and each country decides its own status.
The result is a patchwork. The United States lists 5-MeO-DMT in Schedule I, its most restrictive category. Some countries name it directly in their drug laws, some cover it through analog clauses, and others do not regulate it at all.
The source can matter too. Bufo alvarius is not on any list of controlled species, yet in some places possessing the toad is lawful while possessing its dried secretion is prosecuted as possessing the controlled compound.
Laws and enforcement change, so treat this page as a starting point, check the current law where you are, and speak to a qualified attorney about anything consequential.