About Us
Training
Research
Harm Reduction
Integration Support
5-MeO-DMT Information
5-MeO-DMT Training & Research

About
The FIVE
Institute

Setting the standard for 5-MeO-DMT
harm reduction, ethics, and care through
provider training, education, and research.

2,500+Real-World Outcomes
11+Countries Served
5+Years in Training
Students taking notes during a FIVE Institute training session
A FIVE Institute speaker presenting on stage during a panel discussion
A FIVE Institute facilitator leading a small-group training session
A researcher fitting an EEG cap on a study participant
A facilitator sitting with a group of trainees during a FIVE Institute training
About The FIVE Institute

Who We Are

The FIVE Institute advances 5-MeO-DMT
harm reduction, ethics, and standards of care.

The Institute collaborates with research organizations and academic institutions on naturalistic and clinical studies of 5-MeO-DMT, and provides advisory support for clinical trials and regulatory policy. Through its professional training programs, it prepares clinicians, therapists, and facilitators to work with 5-MeO-DMT safely and responsibly. Its public programs include live seminars, free community integration support, and mini courses.

Our 5-MeO-DMT Ecosystem

The FIVE Institute and its sister organizations operate under Kaivalya Ventures, Inc.

Kaivalya Ventures, Inc.
Why We Exist

Our Mission

To ensure 5-MeO-DMT is introduced to the world safely and responsibly.

The FIVE Institute envisions a future in which the therapeutic and scientific potential of 5-MeO-DMT is responsibly realized. Its approach integrates the experiential knowledge of the field’s most experienced practitioners with current clinical and neuroscientific research, with the aim of building a comprehensive, evidence-based understanding of the compound. In practice, this means training providers to rigorous, evidence-based standards, providing public education, and ensuring that support and resources remain accessible to all who need it.
Explore Our Training →Explore Our Research →
A study participant wearing a high-density EEG cap during a 5-MeO-DMT research session
A researcher preparing EEG electrodes and wiring
A trainee reviewing a medical screening form during a FIVE Institute training

Our Team & Advisors

The FIVE Institute draws on an interdisciplinary team whose expertise spans clinicians, scientists, psychologists, legacy facilitators, and more.

Portrait of Victoria Wueschner, Co-Founder & President, The FIVE Institute
Victoria WueschnerCo-Founder & President
Portrait of Joel Brierre, Co-Founder & CEO, The FIVE Institute
Joel BrierreCo-Founder & CEO
Portrait of Cory Firth, Strategic Development, The FIVE Institute
Cory FirthStrategic Development
Portrait of Dr. Joseph Barsuglia, Clinical Psychologist, The FIVE Institute
Dr. Joseph BarsugliaClinical Psychologist
Portrait of Dr. Greggory Wells, Clinical Psychologist, The FIVE Institute
Dr. Greggory WellsClinical Psychologist
Portrait of Dr. Stephanie Abrams, Neuropharmacologist, The FIVE Institute
Dr. Stephanie AbramsNeuropharmacologist
Portrait of Dr. Manesh Girn, Neuroscientist, The FIVE Institute
Dr. Manesh GirnNeuroscientist
Portrait of Dr. Benjamin Malcolm, Pharmacologist, The FIVE Institute
Dr. Benjamin MalcolmPharmacologist
Portrait of David Drapkin, Therapist, The FIVE Institute
David DrapkinTherapist
Portrait of Otto Maier, Head of Integration, The FIVE Institute
Otto MaierHead of Integration
Portrait of Chad Charles, 5-MeO-DMT Educator, The FIVE Institute
Chad Charles5-MeO-DMT Educator

Partners & Press

Research & Education Partners

We welcome research collaborations, education partnerships, and media inquiries related to 5-MeO-DMT.

Explore Research → Partner With Us →

In collaboration with academic institutions and research organizations, including Imperial College London and University College London (UCL), the Institute conducts naturalistic and clinical studies of 5-MeO-DMT and provides advisory support for clinical and pharmaceutical development.

The Institute also delivers harm reduction education to academic institutions, organizations, and companies in the psychedelic sector. Its work, together with that of its sister company, Tandava Retreats, has received coverage in leading international media.

Partners, Press & Collaborators
Imperial College LondonUniversity College London (opens in a new tab)The University of Utah (opens in a new tab)MINDSUniversité de MontréalQualia Research Institute (opens in a new tab)
Drug Science (opens in a new tab)MAPS Italia (opens in a new tab)The Shulgin FoundationPsychedelic Association of Canada (opens in a new tab)States of Mind (opens in a new tab)DoubleBlind (opens in a new tab)Psychedelic Medicine Association (opens in a new tab)Numinus (opens in a new tab)
Forbes (opens in a new tab)Vogue (opens in a new tab)BuzzFeed (opens in a new tab)The Economist (opens in a new tab)High Times (opens in a new tab)Condé Nast (opens in a new tab)Popular Mechanics (opens in a new tab)Unreported World, Channel 4 (opens in a new tab)RTL Germany
Get Started

Learn With The FIVE Institute

Whether you are a clinician, therapist, facilitator, or researcher, there is a place to begin: professional training, live educational seminars, resources, and community integration support.
Schedule an Admissions Consultation →Explore the Training →