Report a 5-MeO-DMT
Adverse Event.
Help the Field Grow Safer.
connected to a 5-MeO-DMT experience or facilitation,
so the field can learn and grow safer for everyone.
Reviewed by The FIVE Institute · Last reviewed
Disclaimer: 5-MeO-DMT is a Schedule I controlled substance in the United States and is regulated in many jurisdictions. This page is educational and does not condone or encourage its use.
How Reporting Makes the Field Safer
Standards of care improve by recording what went wrong and changing practice in response.
The FIVE Institute’s 5-MeO-DMT adverse event reporting gives the field a confidential, structured way to document harm connected to an experience or facilitation. Every report informs our published safety standards, training curriculum, and harm-reduction resources, for the practitioners, researchers, and future participants who can learn from it.
Adverse-event reports close the loop: real-world outcomes, including the difficult ones, feed the standards the field trains against. Reports also give people who experienced harm a place for it to count.
To learn more about staying safe, see our guides to 5-MeO-DMT harm reduction and risks, cautions & contraindications.
What Counts as an Adverse Event?
If something about your experience caused harm, or still feels wrong, it is worth reporting. Adverse events can include lasting side effects, a difficult or “bad” experience, or reactivations (sometimes called flashbacks). Common examples include:
- Class A · Physical
01
Physical Harm
Injury, a medical emergency, or physical symptoms during or after the experience.
- Class B · Psychological
02
Psychological Distress
Extreme anxiety, panic attacks, destabilization, or psychosis that continues well beyond the session.
- Class C · Critical
03
Threat to Life
Severe depression, suicidality, or an inability to continue holding the emotional content emerging.
- Class D · Reactivation
04
Severe Reactivations
Re-experiencing a 5-MeO-DMT experience, day and night, over many weeks to months.
Why Real-World Reports Matter
A Small Clinical Evidence Base
Most Use Happens Outside Clinics
A Field Still Building Its Data
Submit a Report
Thank you for sharing your experience. Our Adverse Event Reporting project, led by our clinical team, is focused on promoting harm reduction in the emerging 5-MeO-DMT landscape. Every report is a meaningful step toward ensuring that what you experienced happens to far fewer people.
To make a report, please fill out this short initial form. From there, our clinical team will reach out to have you complete an official, HIPAA-compliant survey. Thank you again for your willingness to help shift standards of care in the 5-MeO-DMT field.
- IntakeShare your initial report
Tell us briefly what happened. You don’t need every detail yet.
- Clinical ReviewConnect with our clinical team
Once we receive your report, a member of our clinical team will reach out personally to complete an official, HIPAA-compliant survey with you.
- Standards UpdateHelp shift harmful practices
Your survey informs our safety standards and facilitator training, helping change the practices that cause harm across the field.
In crisis or thinking about suicide? Please don’t wait for a reply. Call your local emergency number, or in the US call or text 988. Elsewhere, find a helpline near you.
- Who sees your report
- Only The FIVE Institute’s clinical team.
- What is required
- Your name, email, the type of experience, and a brief description. You choose how much to share.
- What happens next
- Our clinical team contacts you to complete an official, HIPAA-compliant survey.
- How reports are used
- To inform the field’s safety standards, our harm-reduction resources, and our training standards.