Medical Disclaimer

The FIVE Institute publishes information about 5-MeO-DMT for educational and harm-reduction purposes. Nothing on this website, in our courses, seminars or downloads, is medical, psychological, psychiatric or legal advice, and it does not replace care from a qualified professional who knows your circumstances.

No endorsement of use

5-MeO-DMT is a Schedule I controlled substance in the United States and is regulated in many other jurisdictions. Our content does not condone or encourage the use of any controlled substance. Laws vary by country and region; see our legality guide.

Your health

5-MeO-DMT carries real physical and psychological risks, and some medical conditions and medications make it unsafe. Always consult qualified medical and mental health professionals before making any decision related to your health, and never stop or change a prescribed medication without medical advice. See Risks & Cautions.

Research and accuracy

We cite peer-reviewed research wherever we can, but research on 5-MeO-DMT is still emerging and findings may change. Study results describe groups of people and may not apply to you. Read how we research and review content in our Editorial Standards.

Emergencies and support

If you or someone else is in danger or crisis, contact your local emergency number or crisis line immediately. For free peer support during or after a psychedelic experience in the United States, Fireside Project offers a call and text line; it is a peer support service, not a crisis line.

Training and certification

Completing a FIVE Institute course or certification shows that you completed our training to our standards. It is not a government licence and does not authorise anyone to administer a controlled substance.

Questions can be sent through our contact page.