5-MeO-DMT
in the Press.

Mary Carreón (2026). Eight Truths About 5-MeO-DMT From Two Experts. DoubleBlind.

About: DoubleBlind interviews Joël Brierre and Victoria Wueschner on the intense, short-lived experience, screening and risk, why they favor synthetic over toad-derived 5-MeO-DMT, and concerns about vape pens and combining it with ibogaine.

Ella Ruder (2026). Eli Lilly to Acquire Psychedelic Drug Developer for $2.8B. Becker's Behavioral Health.

About: Eli Lilly agrees to buy AtaiBeckley, developer of an intranasal 5-MeO-DMT treatment for treatment-resistant depression, for about $2.8 billion upfront.

Mark S. Gold, M.D. (2026). From Toad "Venom" Psychedelic to Potential Antidepressant. Psychology Today.

About: How celebrity testimonials drew researchers to 5-MeO-DMT, and how a synthetic form is now in early trials for depression, with promising but preliminary results and serious risks outside controlled settings.

Natan Ponieman (2025). FDA Grants Breakthrough Therapy Designation to Beckley and Atai's 5-MeO-DMT Program. Psychedelic Health.

About: The FDA grants Breakthrough Therapy Designation to BPL-003, an intranasal 5-MeO-DMT for treatment-resistant depression, with phase 3 trials planned for 2026.

Leah Kuntz (2025). Positive Results From the Phase 2b Study of BPL-003 in Patients With Treatment-Resistant Depression. Psychiatric Times.

About: A single dose of intranasal BPL-003 produced rapid, lasting antidepressant effects in treatment-resistant depression in a phase 2b trial.

Josh Hardman (2025). Beckley's 5-MeO-DMT Shows Rapid, Durable Antidepressant Effects in Phase 2b Study. Psychedelic Alpha.

About: Analysis of Beckley Psytech’s phase 2b BPL-003 results in treatment-resistant depression, and how they compare with competitor GH Research.

Heidi Anne Duerr, MPH (2025). Positive Results in Phase 2b Trial of Psychedelic Agent GH001 for Treatment-Resistant Depression. Psychiatric Times.

About: An 81-participant, placebo-controlled phase 2b trial of inhaled mebufotenin (GH001, 5-MeO-DMT) reported rapid, large reductions in depressive symptoms.

Daniel Keane (2024). Could Psychedelic Toads Boost Our Brains? London Scientists Launch Trial Into Substance Found on Amphibian's Skin. Evening Standard.

About: Researchers at Imperial College London begin testing synthetic 5-MeO-DMT to study its effects on the brain and its therapeutic potential.

BCSP Staff (2024). The Secrets of Toad Secretions. UC Berkeley Center for the Science of Psychedelics.

About: Explains a Nature study showing 5-MeO-DMT binds strongly to 5-HT1A and 5-HT2A serotonin receptors, with 5-HT1A activation linked to anti-anxiety and antidepressant effects in mice.

Deborah Balthazar (2023). The Sonoran Desert Toad Can Alter Your Mind — It's Not the Only Animal. Science News.

About: How the Sonoran Desert toad secretes 5-MeO-DMT, and a tour of other animals with mind-altering compounds.

Margaret Osborne (2022). Don't Lick This Toad, National Park Service Says. Smithsonian Magazine.

About: After a National Park Service warning, the toxin’s psychedelic appeal, the pressure collection puts on the toads, and the push for synthetic alternatives.

Juliana Kim (2022). The National Park Service Wants Humans to Stop Licking This Toad. NPR.

About: The National Park Service warns visitors not to lick the Sonoran Desert toad, whose toxic secretions contain 5-MeO-DMT.

Olivia Rosane (2022). The Demand for This Toad's Psychedelic Venom Puts the Species at Risk, Conservationists Warn. EcoWatch.

About: Conservationists warn that rising demand for the Sonoran Desert toad’s secretion, sought for retreats and rituals, could endanger the species.

David Carpenter (2021). Psychedelic Toads Pushed to the Limit, Conservationists Urge Synthetic 5-MeO-DMT Option. Forbes.

About: Conservationists warn that demand for toad secretion is pressuring Sonoran Desert toad populations, and urge synthetic 5-MeO-DMT instead.

Natan Ponieman (2021). Psychedelic Compound 5-MeO-DMT Could Make Therapy Short and Effective: Beckley Psytech Is 'All In'. Benzinga.

About: Beckley Psytech goes “all in” on 5-MeO-DMT as a short, effective psychedelic therapy.

David Carpenter (2021). Researchers in Europe, U.S. Team Up to Produce First Ever 5-MeO-DMT Psychedelic Training Program. Forbes.

About: Researchers in Europe and the U.S. team up on the first 5-MeO-DMT psychedelic training program.

David Carpenter (2021). Three Friends Explore the Obscure and Potent Substance 5-MeO-DMT in This Existentially Intense Film Doc. Forbes.

About: David Carpenter on the documentary 5-MEO, in which three friends explore 5-MeO-DMT.

David Carpenter (2021). GH Research Goes Public to Turn 5-MeO-DMT into Medicine for Treatment-Resistant Depression. Forbes.

About: GH Research goes public to develop 5-MeO-DMT as a treatment for treatment-resistant depression.

David Carpenter (2021). From Hunter Biden to HGTV Star Christina Haack, Psychedelic Toad Venom Hits the Mainstream. Forbes.

About: From Hunter Biden to HGTV’s Christina Haack, how psychedelic toad venom hit the mainstream.

David Carpenter (2020). 5-MeO-DMT: The 20-Minute Psychoactive Toad Experience That's Transforming Lives. Forbes.

About: David Carpenter on 5-MeO-DMT’s brief, intense experience and the people who say it has transformed their lives.

B. David Zarley (2020). Psychedelic Toad Venom Explained. Freethink.

About: An explainer on 5-MeO-DMT: short but intense experiences, and early research into therapeutic uses.

EJ Dickson (2020). Spanish Porn Star Charged With Manslaughter in Connection With Toad Venom Ritual. Rolling Stone.

About: Coverage of a manslaughter charge over the 2019 death of a photographer who smoked toad venom during a ritual, a case cited in harm-reduction discussions.

Julia Naftulin (2019). Mike Tyson Smoked a Drug Derived from Toad Venom. Here's What to Know About the Psychedelic That He Says Makes You Feel Like "You Die and You're Reborn". Insider.

About: What to know about 5-MeO-DMT after Mike Tyson described smoking toad venom.

Eric W. Dolan (2019). A Single Dose of 5-MeO-DMT Produces Rapid and Persistent Improvements in Life Satisfaction and Psychopathological Symptoms. PsyPost.

About: Coverage of a study finding that a single dose of 5-MeO-DMT was followed by rapid, persistent improvements in life satisfaction and psychopathological symptoms.

Larry Gallagher (1994). Smoking Toad. The New York Times Magazine.

About: Larry Gallagher’s 1994 New York Times Magazine feature on smoking the secretion of the Sonoran Desert toad, one of the earliest mainstream reports.

John Semley. I Wanted Ego Death. This Powerful Psychedelic Gave It to Me.. BuzzFeed News.

About: John Semley’s first-person account of seeking ego death with 5-MeO-DMT at a psychedelic retreat.

David Carpenter. Why Are Celebrities Smoking Toad Venom?. InStyle.

About: Why toad venom became a celebrity trend, and what 5-MeO-DMT actually does.

David Carpenter. Hunter Biden's Admission of Toad Venom Use Signals a Sea Change for Addiction Treatments. Lucid News.

About: What Hunter Biden’s admission of toad venom use signals for addiction treatment.

David Carpenter. 5-MeO-DMT: The Story Behind the "God Molecule". DoubleBlind.

About: David Carpenter on the history of 5-MeO-DMT and how it came to be called the “God molecule.”

Gaurav Dubey. When the Drop Rejoins the Ocean: An Evidence-Based & Personal Exploration of 5-MeO-DMT. Microdose.

About: Gaurav Dubey’s evidence-based and personal exploration of the 5-MeO-DMT experience.