Disclaimer: Part of the media library. The FIVE Institute does not necessarily agree with every view expressed in these works.
5-MeO-DMT Essays From the Field
Joël Brierre (2026). 5-MeO-DMT for Mental Health and Transformation. States of Mind.
About: A survey of 5-MeO-DMT’s pharmacology, clinical research, risks, dosing, and legal status, by the co-founder of The FIVE Institute.
Eugene Alliende. Truth of Being. Personal piece.
About: On Being, the ever-present “I Am”, as the one absolute truth, traced through waking life, deep dreamless sleep, and the near-death experience.
EssayEugene Alliende. Living Non-Duality: You Are the Medicine. Personal piece.
About: On integrating nondual realization into everyday life, from nirvakalpa to sahaj samadhi, and the return to the world with helping hands.
EssayEugene Alliende. Bridging Heaven: The Art and Science of Psychedelic Yoga. Personal piece.
EssayEugene Alliende. Physics of Consciousness: Unraveling the Mystery of Existence. Personal piece.
EssayValeria Salas Carrillo. En-theo-gen: A Brief Look Into the Components of Journeying with 5-MeO-DMT. Personal piece.
EssayEugene Alliende. Conversations on the Edge of Hyperspace. Personal conversational piece.
EssayNeil Barnes (2025). Vanishing Point: A 5-MeO-DMT Journey. 150 Dunbar Street (Substack).
About: A first-person account of a 5-MeO-DMT ceremony: ego dissolution, deep grief, laughter, and the ongoing work of becoming.
Read EssayAlex MacCaw (2024). The Toad. Personal blog.
About: Alex MacCaw on his 2018 experience with 5-MeO-DMT on a Mexican beach, and how it shifted his motivation from fear to joy.
Read EssayJulia Christina (2022). Bufo Alvarius, the Toad Medicine That Reveals the Secrets of the Universe. Substack.
About: A first experience that began in terror and ended in profound beauty, and reflections on integrating it.
Read EssayFaust (2020). Revisiting The Toad: A Second Experience With 5-MeO-DMT. Medium.
About: Nearly a year after a first experience, a second session renews the author’s sense of centeredness and how to carry its insights into daily life.
Read EssayCraig Wanless (2019). "I Am Home": My Toad (5-MeO-DMT) Experience. Medium.
About: A ceremony in the Costa Rican jungle, ego dissolution and oneness, and a closing word of caution on choosing facilitators carefully.
Read EssaySeth Lorinczi (2019). Toad and Me, or: Smoking Amphibian Venom for Psycho-Spiritual Health. Medium.
About: A personal essay on smoking 5-MeO-DMT in a therapist’s office, and the lasting effects of the experience.
Read Essay
Start With Foundations 101
A self-paced, one-hour mini-course with key understandings for those newer to 5-MeO-DMT, with a desire to go deeper.