Disclaimer: Information shared by seminar speakers does not necessarily represent the views of The FIVE Institute, and The FIVE Institute is not responsible for inaccurate information shared by guest speakers. 5-MeO-DMT is a Schedule I controlled substance in the United States and is regulated in many jurisdictions. These recordings are educational and do not condone or encourage its use.
Latest Seminar Recording
5-MeO-DMT for the Scientific Study of Consciousness
With Dr. Christopher TimmermannCo-Director, UCL Centre for Consciousness Research
An in-depth exploration with Dr. Chris Timmermann of 5-MeO-DMT, ego dissolution, neuroscience, meditation, and the scientific study of consciousness.
What you'll learn
Why consciousness is central to the study of psychedelics
How 5-MeO-DMT differs from DMT in subjective experience and brain activity
Ego dissolution, "pure awareness" and the "everything and nothing" state, and what they reveal about the sense of self
With Dr. Robin Carhart-Harris, Dr. Manesh Girn, and Tommaso Barba
Our panel discusses what current research is revealing about how 5-MeO-DMT may affect the brain differently from other psychedelics such as N,N-DMT, psilocybin, and LSD.
Field researcher Dr. Malin Vedoy Uthaug explores what her research is revealing about transformation through the lens of physiology, regulation, and the body's capacity to adapt.
An in-depth exploration with Dr. Chris Timmermann of 5-MeO-DMT, ego dissolution, neuroscience, meditation, and the scientific study of consciousness.
Ego DissolutionNeuroscience & Meditation
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Watch the Recordings
The Seminar Archive
Free recordings of every FIVE 5-MeO-DMT seminar, from neuroscience and consciousness research to safety, harm reduction, psychotherapy and integration, taught by the field’s leading researchers, clinicians and facilitators.
Why the evidence for ancient, ancestral use of Bufo alvarius secretion is far shakier than often claimed, and where the stronger archaeological record actually points
How 5-MeO-DMT behaves differently from other tryptamines, including amnesia, loss of awareness and anesthetic-like effects
What the "dreaded underdose" is and why lower doses are not automatically gentler
Simple safety steps that prevent common harms, such as fasting beforehand to avoid vomiting while unconscious
Why the toad secretion is essentially just 5-MeO-DMT, and what that means for the synthetic-versus-toad debate
Live Q&A on dosing, set and setting, and emerging EEG and EKG research
Bodyset, the state of the body, and why it matters as much as mindset
Catharsis: when release is healing, and when it is a nervous-system red flag
Pivotal Physical States (PiPS): extreme or transitional physiological conditions that can lead to healing or trauma depending on adaptability and regulation
What practitioners, facilitators and serious seekers should understand about integration as a bodily process
The FIVE 9-month 5-MeO-DMT Facilitator Training brings these researchers, clinicians and facilitators together into one rigorous program. Talk with our admissions team about whether it is the right fit for you.