Seminar Recording · Safety & Neurobiology

5-MeO-DMT, Psychedelics & Psychosis

With Haley Maria Dourron

An examination of the atypical neurobiological and phenomenological risks associated with 5-MeO-DMT, including reactivations, seizure-like activity, and why this compound cannot be understood or communicated like other psychedelics.

What you'll learn

  • Why 5-MeO-DMT is pharmacologically and phenomenologically distinct from classical psychedelics
  • What "reactivations" are, how they differ from HPPD, and why terminology matters
  • Evidence linking 5-HT1A-dominant activity to seizure-like and dissociative phenomena
  • How route of administration, dosing patterns, and metabolism may influence risk

SafetyNeurobiologyReactivations

Information shared by seminar speakers does not necessarily represent the views, thoughts, and opinions of The FIVE Institute.