Groundbreaking Research
& Real-World Impact.
Discover how real-world evidence and high-impact partnerships fuel groundbreaking 5-MeO-DMT research and support the setting of new standards for psychedelic science.
The owner of this website, F.I.V.E. is providing educational training to educate, inform, and promote harm reduction. The educational training has not been evaluated by the FDA. 5-MeO-DMT should not be used to diagnose, treat, cure or prevent any disease or condition. F.I.V.E. does not endorse or promote the use of 5-MeO-DMT and does not encourage or condone any illegal activities.
How Research
Drives Us Forward
At the heart of our mission lies a commitment to advancing the understanding of 5-MeO-DMT through rigorous research. Real-time evidence collected at our Tepoztán institute allows us to refine and improve our educational programs, ensuring they are grounded in the latest insights and best practices. We believe that research is essential not only for safety and efficacy but for expanding the understanding and accessibility of 5-MeO-DMT in therapeutic settings.
Our Unique Approach
What sets our research apart in our unique ability to conduct real-time, real-word studies at our Tepoztlán institute. This on-site capacity provides immediate feedback and insights, enabling us to adapt and refine our approach quickly. Combined with our global partnerships, this research model allows us to contribute high-quality, actionable data that supports the safe and effective use of 5-MeO in various therapeutic contexts.
Research on 5-MeO-DMT, offers unique insights into the nature of consciousness. Its effects on the brain, such as altering neural connectivity and suppressing activity in the default mode network, allow researchers to explore how self-awareness and the sense of individuality are constructed. These studies may illuminate the neural basis of mystical or transcendent experiences, shedding light on how the brain processes non-ordinary states of consciousness. Understanding these mechanisms could help bridge gaps between neuroscience, psychology, and philosophy in the quest to comprehend the full spectrum of human awareness.
Research into 5-MeO-DMT, has the potential to address significant gaps in mental health therapy. Unlike traditional treatments, which often require prolonged use, 5-MeO-DMT has shown promise in fostering transformative psychological insights and emotional breakthroughs in a single or a few sessions alongside therapy. Emerging studies suggest its potential for treating conditions like depression, PTSD, and anxiety, especially for patients resistant to conventional therapies. By expanding our understanding of its mechanisms, safety, and efficacy, this research could revolutionize mental health care and provide new hope for those in need.
The Role Research Plays
In Our Training
Our educational offerings are directly shaped by ongoing research, allowing us to provide students and healthcare professionals with up-to-date protocols and safety standards. Each insight gathered from our studies becomes a building block in training practitioners to work confidently with 5-MeO-DMT, bridging the gap between theoretical knowledge and hands-on application.
Research Partnerships
We proudly collaborate with world-leading institutions, bringing together pioneering minds to unlock new applications for 5-MeO. These partnerships enrich our work, offering invaluable expertise and resources that help propel the field forward. Together, we are committed to setting a high standard for psychedelic research, ensuring it is both ethically sound and scientifically robust.
Join Us in Advancing 5-MeO-DMT Research
Are you interested in partnering to drive forward groundbreaking research in 5-MeO-DMT safety and efficacy? Connect with us to explore how we can work together to puch the boundaries of what is possible.



